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pentobarbital will minimize the level or outcome of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers haven't been studied, coadministration not advisable by manufacturer
fentanyl transmucosal and pentobarbital both of those raise sedation. Stay away from or Use Alternate Drug. Limit use to clients for whom option treatment method possibilities are insufficient
pentobarbital will lessen the extent or impact of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
fentanyl intranasal and pentobarbital both equally increase sedation. Prevent or Use Alternate Drug. Restrict use to patients for whom choice treatment method choices are insufficient
Consistently check vital indicators during sedation and Restoration period if coadministered. Very carefully titrate remimazolam dose if administered with opioid analgesics and/or sedative/hypnotics.
pentobarbital will minimize the level or outcome of pitolisant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Pitolisant exposure is reduced by fifty% if coadministered with solid CYP3A4 inducers.
pentobarbital will lessen the level or impact of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lessen the level or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will reduce the level or impact of abiraterone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Contraindicated (1)pentobarbital will lessen the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women must not choose estradiol valerate/dienogest as their more info contraceptive even though employing solid CYP3A4 inducers resulting from possible minimize in contraceptive efficacy.
pentobarbital will reduce the level or effect of lopinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Observe Carefully (2)pentobarbital will lessen the extent or outcome of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Potent CYP3A4 inducers could minimize suvorexant efficacy; if elevated suvorexant dose demanded, tend not to exceed 20 mg/day
Reserve concomitant prescribing of these medicine in individuals for whom other treatment choices are insufficient. Limit dosages and durations to the minimum expected. Observe carefully for signs of respiratory depression and sedation.
pentobarbital will lower the extent or effect of voriconazole by affecting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Not known.